Today our topic of discussion is Chorionic Villi Biopsy.
Chorionic Villi Biopsy
CHORIONIC VILLI BIOPSY
Chorionic villi biopsy (CVB) can detect early abnormalities. Fetal cells are obtained by section from finger like projections around the embryonic membrane, which eventually becomes the placenta. The test is performed between the eighth and tenth weeks of pregnancy.
After the tenth week, maternal cells begin to grow over the villi. The advantages of CVB over amniocentesis are that CVB may be performed earlier, and results can be obtained in a few days and not weeks. CVB can diagnose many chromosomal and bio-chemical fetal disorders (Fig. 33.2).
Purposes
To detect chromosomal discharges.
Indications
- Chromosomal disorders
- Hemoglobinopathies, such as sickle cell anemia, lysosomal storage disorders, such as Tay-Sachs disease.
Client Preparation
- Obtain a history of last menstrual period (LMP) from the client and a history of family genetic disorders
- Assess for signs of spontaneous abortion resulting from procedure, such as cramping, bleeding
- Assess for infection resulting from procedure, such as chills, fever
- Be supportive of client and family. Be good listener.
Procedure
- A consent form should be signed
- There are no food and fluid restrictions
- Place the client in the lithotomy position
- Ultrasound is used to verify the placement of the catheter at the villi.
- Suction is applied, and tissue is removed from the villi
- Test takes approximately 30 minutes.
Factors Affecting Diagnostic Results
Performing test after 10 weeks of gestation.
Client Teaching
- Explain to the client that she will be in a lithotomy position and that ultrasound is used during the procedure
- Instruct the client to report if excessive bleeding or severe cramping occurs after procedure.
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