Concept About IUCD | CHAPTER-17 | Pharmacology

Concept About IUCD – This book covers the entire syllabus of “Pharmacology” prescribed by BNMC- for diploma in nursing science & midwifery students. We tried to accommodate the latest information and topics. This book is an examination setup according to the teachers’ lectures and examination questions.

At the end of the book, previous questions are given. We hope in touch with the book students’ knowledge will be upgraded and flourish. The unique way of presentation may make your reading of the book a pleasurable experience.

Concept About IUCD

Definition of IUCD:

Intrauterine contraceptive device is a small plastic carrier, usually in the shape of a T or similar design on the vertical stem of which is wound some copper wire and may have copper bands on the transverse arms.

Or,

An IUD is a small, T-shaped plastic device that is wrapped in copper or contains hormones. The IUD is inserted into the uterus by a doctor. A plastic string tied to the end of the IUD hangs down through the cervix into the vagina.

(Ref by: D. C. Dutta’s Gynae/7/397)

 

Concept About IUCD | CHAPTER-17 | Pharmacology

 

Mechanism of Action of IUCD/Copper-T:

A. Foreign body inflammatory reaction on the endometrium cases:

  • Increase PG secretion
  • Inflammatory cells- Leucocytes and macrophages in the edometrium make a hostile
  • environment for fertilized ovum and phagocytose the sperm and blastocyte. Increase tubal motility which result in quick migration of the fertilized ovum into the uterine cavity before the endometrium is receptive.

B. Cooper ion causes:

  • Interferes with all the enzymatic activity of endometrium, particularly Zn containing carbonic anhydrase
  • Interferes with cellular DNA control
  • Increase inflammatory uptake by endometrium
  • Toxic effect of Cu affects sperm motility, capacitating and survival by altering the biochemical composition of cervical mucus

a. Ist generation- Lippes loop.

b. 2nd generation-> Cu impregnant CuT

c. 3rd generation->Hormone impregnant ->Progestasent.

d. Hospital supply -> Cu 1200

(Ref by: D. C. Dutta’s Gynae/7h/398)

Definition of Copper – T:

A small, “T” shaped plastic device inserted into the uterus by medical personnel to prevent pregnancy.

contraindication and adverse effect of IUCD.

A. Indication of Cu-T:
  • Multiparous women for birth spacing
  • Women who cannot use hormonal contraceptive methods.
  • Contraceptive method for lactating mother
  • Post coital contraception when IUCD is inserted within 5 days of unprotected sex.
  • Unreliable, illiterate woman when patient compliance is not good to pill.
B. Contraindication of Cu-T:a) Absolute:

  • Suspected pregnancy
  • PID
  • Vaginal bleeding of unknown aetiology.
  • Cancer of the cervix, uterus or adnexia and other pelvic tumors.
  • Previous ectopic pregnancy.
  • Wilson’s diseases.
  • Gynocologic or breast malignancy

b) Relative:

  • Anaemia
  • Menorrhagia
  • H/O PID since last pregnancy
  • Purulent cervical discharge.
  • Distortion of the uterine cavity due to congenital malformation, fibroids.
  • Unmotivated person.
C. Side effect:
  • Mood changes
  • Acne
  • Headache
  • Breast tenderness
  • Nausea
  • Cramping and pain at insertion
  • Increased bleeding
  • Pelvic infection
  • Uterine perforation
  • Expulsion
  • Ectopic pregnancy

 

Complication of Copper-T:

1. Fainting and collapse of the patient

2. Mood changes

3. Acne

4. Headache

5. Breast tenderness

6. Nausea

7. Cramping and pain at insertion

8. Increased bleeding

9. Pelvic infection

10. Uterine perforation

11. Expulsion

12. Ectopic pregnancy

(Ref by K. Park/22/497)

A. Advantages of Cu – T/IUCD:
  • High effective.
  • No known systemic side effects
  • Nearly always reversible.
  • In-expensive.
  • Independent of intercourse.
  • Simple procedure in insertion. No need of hospitalization or day to day action like pill.
  • Once inserted Cu-T stays in place as long as required.
  • Does not influence milk volume, lactation or composition of milk.
  • Highest continuation report.
  • Useful in illiterate or ignored people.
B. Disadvantages of IUCD:1. Not 100% effective (only 97%)
2. Increase menstrual bleeding:

  • Menorrhagia.
  • Dysmenorrhoea.
  • Inter-menstrual bleeding
  • Anaemia.

3. Pregnancy- 60th intrauterine and ectopic pregnancy.
4. Pain & discomfort- low backache, lower abdominal cramp, pain in the thigh.
5. Perforation of uterus.
6. Pelvic inflammatory diseases:

  • High risk of salphingitis.
  • Endometritis.
  • Vaginal discharge with pain, fever, chill.
  • PID may lead to permanent sterilization.

7. Syncopal attack.
8. Cramp like pain
9. Expulsion with risk or pregnancy.
10. Thread to infertility.
11. Infection – actinomyces israeliae

 

(Ref by K. Park/22/498+Neuron Gynaecology)

Best Time of Insertion:

1. End of menstruation

2. 6 weeks after delivery or abortion

3. Just after MR.

4. Insertion by withdrawal method.

5. Follow up: After each mens.

 

Concept About IUCD | CHAPTER-17 | Pharmacology

 

Advice or Instructions for Cu-T Users:

1. She should regularly check the threads or tails to be sure that the Cu-T is in the uterus, if she fails to locate the threads, she must consult the doctor.

2. She should visit the clinic whenever she experiences any side effects such as fever, pelvic pain and bleeding.

3. If she misses a period, she must consult the doctor.

4. She should be examined after her 1st menstrual period, for the chances of loop expulsion are high during this period, and again after the third menstrual period to evaluate the problems of pain and bleeding, and thereafter at six month or one year intervals depending upon the facilities and the convenience of the patient.

Selection of Patient for IUCD:

A. Patient profile

  • Age of the patient.
  • She should have at least one child

B. History:

  • History should be taken to exclude menstrual abnormality, PID, previous history of ectopic pregnancy and suspected pregnancy.
  • Personal history

C. Pelvic examination:

  • To determine-the size, shape position and mobility of the uterus.
  • To exclude adnexal and cervical pathology

D. Investigation:

  • Pregnancy test to exclude pregnancy. Cervical smear may be taken if possible

E. Counseling:

  • It is essential to discuss the possible side effects of these preparations with each woman before administration & should be advised for follow up visits.

(Ref: D. C. Dutta’s Gynae/7/398)

Missing IUCD.

The threads of the IUCD sometime not palpable by the user. It may be –

a. Device in uterus but

  • Thread cut too short or caught up around the device
  • Avulsed at a previous removal attempt
  • Device itself mal-positioned or translocation inside the uterus

b. Translocation into the abdomen (by perforation of uterus) –

  • In the broad ligament
  • Peritoneal cavity

c. Expulsion

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Diagnosis of the missing/displacement of IUCD:

A. Examination:

  • Abdominal palpation
  • Speculum examination
  • Introduction of uterine sound inside the uterus

B. Investigation:

  • X-ray pelvis A/P and straight lateral view
  • Ultrasonography
  • Hystero salphingography
  • Hysteroscopy
  • Laparoscopy

C. Management:

a) When IUCD is inside the uterus –

  • Remove the IUCD by thread retrievers of by D & C

b) When IUCD is outside the uterus remove the IUCD by –

  • Laparotomy
  • Laparoscopy

(Ref by: D. C. Dutta’s Gynae/7/398)

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