Concept About Oxytocin – This book covers the entire syllabus of “Pharmacology” prescribed by BNMC- for diploma in nursing science & midwifery students. We tried to accommodate the latest information and topics. This book is an examination setup according to the teachers’ lectures and examination questions.
At the end of the book, previous questions are given. We hope in touch with the book students’ knowledge will be upgraded and flourish. The unique way of presentation may make your reading of the book a pleasurable experience.
Concept About Oxytocin
Contraindication of oxytocin
- Oxytocin injection (synthetic) is contraindicated in any of these conditions:
- Substantial cephalopelvic disproportion
- Unfavorable fetal position or presentation (e.g., transverse lies) undeliverable without conversion before delivery
- Obstetric emergencies where maternal or fetal risk-to-benefit ratio favors surgery
- Fetal distress when delivery is not imminent
- Umbilical cord prolapse
- Uterine activity fails to progress adequately
- Hyperactive or hypertonic uterus
- Vaginal delivery is contraindicated (e.g., invasive cervical carcinoma, active genital herpes infection, total placenta previa, vasa previa, cord presentation or prolapse)
- Uterine or cervical scarring from previous cesarean section or major cervical or uterine (e.g., transfundal) surgery
- Unengaged fetal head
- History of hypersensitivity to oxytocin or any ingredient in the formulation

Allergic reactions
Allergic reactions are sensitivities to substances called allergens that come into contact with the skin, nose, eyes, respiratory tract, and gastrointestinal tract. They can be breathed into the lungs, swallowed, or injected,
Drug’s Use for Allergic Reaction:
➤Antihistamines
- Acrivastine
- Carbinoxamine
- Cyproheptadine
- Desloratadine
- Hydroxyzine
- Levoceterizine
➤ Corticosteroids
- Prednisone
- Prednisolone
- Cortisol
- Methylprednisolone
➤ Leukotriene Inhibitor
- Montelukast
➤ Topical Immunomodulators
- Tacrolimus
- Pimecrolimus
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