Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) – This book covers the entire syllabus of “Pharmacology” prescribed by BNMC- for a diploma in nursing science & midwifery students. We tried to accommodate the latest information and topics. This book is an examination set up according to the teachers’ lectures and examination questions.
At the end of the book, previous questions are given. We hope in touch with the book students’ knowledge will be upgraded and flourish. The unique way of presentation may make your reading of the book a pleasurable experience.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Anti-Inflammatory Drug is a drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation. They are used to treat many different conditions. Some anti-inflammatory agents are being studied in the prevention and treatment of cancer.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs):
The agents that produce analgesia without producing generalized depression of CNS and addiction are known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are so called because they show:
1. Analgesic action.
2. Anti-inflammatory action
3. Anti-pyrectic action
4. Anti-platelet action
By inhibiting the synthesis and release of prostaglandin.
Classification/Name of NSAIDS
A. According to their anti-inflammatory action:
➤ Drugs with analgesic but with negligible anti-inflammatory action:
- Acetaminophen (paracetamol)
- Phenacetin
➤ Drugs with analgesic & mild to moderate anti-inflammatory action:
a. Propionic acid derivative:
- Ibuprofen
- Ketoprofen
- Naproxen
- Indoprofen
b. Fenamates:
- Flulfenamic acid
- Meclofenamic acid
b. Nabumetone
B. Drugs with analgesic and strong anti-inflammatory action:
a. Salicylic acid derivatives:
- Acetyl salicylic acid
- Sodium salicylate
- Benorylate
- Diflunisal
b. Acetic acid derivative:
- Diclofenac
- Indomethacin
c. Pyrazolone derivative:
- Phenylbutazone
d. Oxicam derivatives:
Piroxicam.
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